Identification of Proteins Interactions at Blood/Artificial Kidney Material Interfaces;Relation to Platelets and WBC.

摘要

The year's findings of general interest were:that platelets in whole blood may adhere to surfaces via reactions not occurring in fibrinogen-free plasma;and that white blood cells may adhere more where fibrinogen had been adsorbed and where platelets had been deposited. Examples of this year's findings related to actual use of dialyzers are the following. Cuprophane appeared neither in vitro nor during actual use,to adsorb fr. XII activity. A certain polypeptide membrane inhibited clotting but if not treated with ionene chloride it adsorbed fibrinogen and white cells adhered. For other membranes,see summary.