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Antithrombogenic Surfaces:Platelet-Interface Reactions.

机译:抗血栓形成表面:血小板界面反应。

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Work has proceeded in six different areas. (1) An in vitro test system for exposure of native blood to dialysis membranes in the absence of other artificial surfaces has been devised and evaluated. (2) A study has been made of the plasma proteins which adsorb to Cuprophane and other artificial surfaces. (3) A study has been made of the adhesion of platelets to Cuprophane and other artificial surfaces. (4) Certain artificial surfaces were shown to activate Factor XI on the platelet plasma membrane. (5) Test devices exposed to flowing blood in arteriovenous shunts in rhesus monkeys were used to evaluate the antithrombotic effects of a number of pharmacologic agents. (6) Human endothelial cells were shown to grow in tissue culture upon Cuprophane,polyethylene,and polystyrene.

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