Synthesis and Purification of Carcinogenic Polynuclear Aromatic Hydrocarbon Standards.

摘要

Experimental work was performed with the objective of preparing six condensed polynuclear hydrocarbons at a purity equal to or exceeding 99.9+%. The compounds to be prepared were benzo(a) pyrene,benzo(a) anthracene,benzo(e) pyrene, chrysene,benzo(b)fluoranthene,and benzo(k)fluoranthene. At the time the contract was terminated, chrysene was the only compound whose quantity and purity has been shown to meet the specifications. Four other compounds,benzo(a) pyrene,benzo(e) pyrene,benzo(b)fluoranthene,and benzo(k)fluoranthene were in process of purification and synthesis. Experimental details as well as analytical methods and safety procedures developed during the course of the work are described.