Microfiber Materials for Growth of Intimal Linings in Circulatory Assist Devices.

摘要

Research efforts continued on the development of microfiber scaffolding for the in-growth of neointimal tissue to achieve blood compatibility with the internal surfaces of circulatory assist device parts. During this period,the intended thrust was the production of microfiber lined Tecothane axisymmetric Model X blood pump bladders, employiny previously developed techniques,for use by evaluators. While the principal bladder lining approach has continued to involve eversion and the use of an additional adhesive,it was necessary during the period to develop a new microfiber lining type,as it was realized that type E would not promote a suitable level of cellular adhesion of the neointimal tissue. The new lining,type G,is a composite of vertically drafted fabrics. In ground work studies for future linings, a novel single layer precursor tape has been manufactured by the lay-flat tubular film process,and a proprietary microfiber pulping technique has been assessed as a potentially useful step in the lining of complex shapes.