An Implantable Controlled Solenoid Left Ventricular Assist System.

摘要

Continued characterization of the functional and endurance capabilities of the MK19Left Ventricular Assist System (LVAS) and development of the MK20 LVAS are described. The MK19system has accumulated a total of 10,000hours of testing. A five-fold improvement in performance has been achieved for the critical bearings and in excess of an order of magnitude for the latch. Significant improvements have been made to the MK19Electronic Control and Power (ECP) subsystem in the areas of energy tracking,servo feedback compensation,system stability and reliability. Conceptual development of the MK20 ECP was initiated utilizing a microprocessor-based control concept. A major effort has been directed at improving the in vitro and in vivo test facilities. A sophisticated data acquisition and reduction system has been built around a dedicated mini-computer providing a powerful capability for real-time hemodynamic monitoring of instrumented animals and off-line presentation of reduced data. This period has been highlighted by the initiation of chronic animal experiments. Four acute and eleven chronic experiments have been carried out in the current period. The mean duration of the last six chronic experiments has been 24days.