Reliability of Bacterial Mutagenesis Techniques to Distinguish Carcinogenic and Noncarcinogenic Chemicals.

摘要

Investigations were conducted to determine the reliability with which an expanded Salmonella mutagenesis test system can distinguish between those organic chemical substances that cause cancer in laboratory animals (presumptive carcinogens) and those that do not (noncarcinogens). The results of such tests of 100organic compounds (50 presumptive carcinogens and 50 noncarcinogens) are described.