Low- and High-Resolution Gas-Chromatography-Mass Spectrometry (GC-MS) Method of Analysis for the Presence of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) in Environmental Samples

摘要

An environmental monitoring project is being conducted to determine if TCDD is accumulating in the environment. TCDD is an extremely toxic, chlorocrigenic, and teratogenic material and is a possible contaminating by-product in manufacturing processes utilizing tetrachlorbenzene and in the manufacture of herbicides containing esters of 2,4,5-trichlorophenoxy acetic acid. The single oral LD(50) of this compound in certain species of guinea pigs is six hundred parts per trillion (600 ppt).