首页> 美国政府科技报告 >N-Acetyl-Cysteine Protects Against Cardiac Damage from Subsequently-Administered Cardio-Toxic Anthracycline in Cancer Therapy

【24h】

N-Acetyl-Cysteine Protects Against Cardiac Damage from Subsequently-Administered Cardio-Toxic Anthracycline in Cancer Therapy

机译：N-乙酰半胱氨酸可预防癌症治疗中随后给予的心脏毒性蒽环类药物对心脏的伤害

获取原文

页面导航

摘要
著录项
引文网络
相似文献
相关主题

摘要

The cardiac damage, occurring after treatment with an anthracycline, such as adriamycin, is prevented when N-acetyl-cysteine is orally administerd about one hour prior to the treatment with the antracycline.

著录项

作者
Myers, C. E. ; Doroshow, J. H. ; Locker, G. Y.;
展开▼
作者单位

展开▼
年度 1979
页码 1-13
总页数 13
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Malignant neoplasms; Patent applications; Drug therapy; Heart;

机译：恶性肿瘤;专利申请;药物治疗;心脏;

相似文献

外文文献
中文文献
专利

1. Long-term efficacy analysis of the randomised, phase II TRYPHAENA cardiac safety study: Evaluating pertuzumab and trastuzumab plus standard neoadjuvant anthracycline-containing and anthracycline-free chemotherapy regimens in patients with HER2-positive early breast cancer [J] . Schneeweiss Andreas, Chia Stephen, Hickish Tamas, European journal of cancer: official journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR) . 2018,第期

机译：随机，II期Tryphaena心脏安全研究的长期疗效分析：评估腹膜和曲妥珠单抗加上标准的新辅助蒽萘萘霉素和无蒽环类化疗中的Her2阳性早期乳腺癌
2. Pertuzumab plus trastuzumab in combination with standard neoadjuvant anthracycline-containing and anthracycline-free chemotherapy regimens in patients with HER2-positive early breast cancer: a randomized phase II cardiac safety study (TRYPHAENA) [J] . Schneeweiss A., Chia S., Hickish T., Annals of oncology: official journal of the European Society for Medical Oncology . 2013,第9期

机译：帕妥珠单抗联合曲妥珠单抗联合标准新辅助含蒽环类和无蒽环类化疗方案治疗HER2阳性早期乳腺癌的患者：一项随机II期心脏安全性研究（TRYPHAENA）
3. Pertuzumab plus trastuzumab in combination with standard neoadjuvant anthracycline-containing and anthracycline-free chemotherapy regimens in patients with HER2-positive early breast cancer: a randomized phase II cardiac safety study (TRYPHAENA) [J] . Schneeweiss A., Chia S., Hickish T., Annals of oncology: official journal of the European Society for Medical Oncology . 2013,第9期

机译：帕妥珠单抗联合曲妥珠单抗联合标准新辅助含蒽环类和无蒽环类化疗方案治疗HER2阳性早期乳腺癌的患者：一项随机II期心脏安全性研究（TRYPHAENA）
4. Clinical implications of HER-2 and p53 in taxane-based and anthracycline-based neoadjuvant chemotherapy in breast cancer [C] . World congress on breast diseases . 2008

机译：HER-2和P53在紫杉烷基和蒽环类新辅助化疗的乳腺癌中的临床意义
5. Transfusional iron, anthracyclines and cardiac outcomes in childhood cancer survivors [D] . Ruccione, Kathleen 2013

机译：儿童癌症幸存者中的输血铁，蒽环类和心脏病蛋白
6. Neurohormonal Blockade and Circulating Cardiovascular Biomarkers During Anthracycline Therapy in Breast Cancer Patients: Results From the PRADA (Prevention of Cardiac Dysfunction During Adjuvant Breast Cancer Therapy) Study [O] . Geeta Gulati, Siri L. Heck, Helge Røsjø, -1

机译：乳腺癌患者蒽环类药物治疗期间的神经激素阻断和循环心血管生物标志物：PRADA（辅助乳腺癌治疗期间预防心功能不全）研究的结果
7. P1246Age-, body size-, and sex-specific reference values for tricuspid valve apparatus parameters by real-time three-dimensional transthoracic echocardiographyP1247Surgical therapy in infective endocarditis: predisposing and prognostic factorsP1248Evalutation of MV annulus geometry modifications before and after mitraclip implantation with 3D transesophageal echocardiographyP1249Prognostic echocardiographic parameters for successful transcatheter edge-to-edge mitral valve repairP1250Influence of body surface area in diagnosis and outcome patient-prosthesis mismatch after TAVI. Is it necessary to adjust for ideal body weight?P1251Outcome of paradoxical low-flow low-gradient severe AS following TAVI: paradoxical VS parallel to outcome of high gradient ASP1252Prognostic role of cardiac calcifications in subjects without overt significant heart disease and previous cardiovascular events: is there an additive value over cardiovascular risk factors scores?P1253Aging degeneration of mitral valve without leaflet prolapse or tethering as a cause of severe mitral regurgitationP1254Cardiovascular risk assessment should be performed in patients with incidental aortic sclerosisP1255Cardiac valve calcification score: simple 2D echocardiographic tool for cardiovascular risk stratification in patients with chronic renal failureP1256Diastolic mitral regurgitation following transcatheter aortic valve replacement: prevalence, predictors and impact on outcomesP1257Timing of myocardial shortening determines left ventricular regional remodelling in hearts with conduction delaysP1258Myocardial stiffness assessment using shear wave imaging in healthy children and hypertrophic cardiomyopathyP1259Assessment of right ventricular response to exercise using vector velocity imaging in hypertrophic cardiomyopathyP1260Diagnostic value of cardiac biomarkers (high sensitive troponin T and N-terminal pro-brain natriuretic peptide) in patients with infiltrative cardiomyopathiesP1261Right ventricular global longitudinal strain differentiates between adolescent patients with definite, borderline and possible ARVC and controlsP1262 echogrqphic predictif factors of atrial arrhythmias in patients with arrhythmogenic right ventricular dysplasiaP1263Importance of combined left atrial size and estimated pulmonary pressure for clinical outcome in patients presenting with heart failure with preserved ejection fractionP1264Chronotropic response in mitochondrial (ANT1) cardiomyopathyP1265 The effect of cardiovascular risk factors and cancer type in anthracycline's cardiotoxicityP1266Revisiting the echocardiographic features of acute myocarditisP1267Altered circulation in fetuses of diabetic mothers: a fetal computational model analysisP1268Increased epicardial adipose tissue is related to stress-induced cardiomyopathyP1269Contrast enhanced ultrasound of kidney perfusion in patients with renal artery stenosis: diagnostic and prognostic applications. [O] . F. Ancona, R. Ilhao Moreira, V. Lavanco, 2016

机译：P1246age-，身体大小和性别特异性参考Tricuspid阀装置参数通过实时三维经线性超声心动图124772777777747774747478EVALIGUTALMEXP1249预期植入前后MV环形植入前后MV环空性修饰。超声心动图参数用于成功的经截管边缘到边缘二尖瓣修复P1250中的体表面积诊断和结果患者假体在Tavi后的不匹配。是否有必要调整理想的体重？P1251矛盾的低流量低梯度严重，如Tavi：矛盾的VS平行于高梯度ASP1252的结果，在没有明显显着的心脏病和以前心血管事件的情况下心脏钙化的促傲作用患有心血管危险因素的添加剂值分数？没有传单脱垂的二尖瓣退化或作为严重二尖瓣血管血管血管病风险评估的患者进行脱垂或系绳，应当在偶然主动脉源肺源P1255Cariac阀钙化评分患者中进行：用于心血管风险分层的简单2D超声心动图工具在慢性肾功能衰竭的患者中，经沟管主动脉瓣膜置换术后：流行率，预测因子和对Otcomasp1257的影响，心肌缩短决定了导通延迟的心中的剩余心室区域重新耦合258MYCIARIAL僵硬评估使用剪切波成像在健康儿童和肥厚性心肌脑病中的舒缓性心脏响应，在渗透心肌肌瘤患者中使用载体速度成像的培养速度成像（高敏感的肌钙蛋白T和N-末端脑Natrietic肽）渗透心肌病，患者心室全局纵向菌株在患有心律失常右心室发育不良患者的心理心律失常患者中的青少年患者与Controlsp1262 echogrqphic预测因子的分歧，患者心血性右心室发育不良患者患者患者患者患者患者患者患者患者患者线粒体（ANT1）心肌病患者的喷射FRACTIONP1264系列响应1265心血管危险因素和癌症类型在蒽丙烯的心肌毒性皮1126660中的影响访问患有糖尿病母亲胎儿胎儿急性心肌炎的超声心动图，患者患者：胎儿计算模型分析P1268增加外膜脂肪组织与肾动脉狭窄患者肾脏灌注的应激诱导的心肌病，增强超声波：诊断和预后应用。

N-Acetyl-Cysteine Protects Against Cardiac Damage from Subsequently-Administered Cardio-Toxic Anthracycline in Cancer Therapy

摘要

著录项

引文网络

相似文献

相关主题

期刊订阅