Development of Air Sampling and Analytical Methods for Toxic Chlorinated Organic Compounds: Research Report for Monochloroacetic Acid

摘要

Methods for determining hexachlorobutadiene, hexachlorocyclopentadiene, 1,2-dichloropropane, monochloroacetic-acid, pentachloroethane and p-chlorophenol in workplace air were developed. For each compounds an analytical method was devised based on selection and calibration of the method; determination of desorption efficiencies of the compound from candidate solid sorbents by solvent extraction; construction and evaluation of an analyte test atmosphere generator and sampling system; determination of the capacities of candidate sorbents for the compound; selection of the sorbent; determination of the stability of the compound when collected from air with the chosen sorbent and determination of the accuracy and precision of the analytical procedure and of the total sampling and analytical method. Each method was tested and modified until the results were considered valid. The author recommends that the effort required per compound, the cost effectiveness of experimental design, field testing of the developed method, and usefulness of research reports be considered for future methods development.