Safety and Antigenicity of Respiratory Vaccines; Epidemiology, Ecology, Pathogenesis of Respiratory Infections; National Influenza Studies

摘要

Since 1962 the authors have administered 24 different candidate inactivated and attenuated respiratory viral vaccines to a total of 451 infants and children. There have been 2099 accumulated years of follow-up on the vaccinees. Although none of these vaccines has been an ideal candidate, the studies have brought out major principles applicable to further development of such vaccines.