Immunologic Cross-Reactivity of Antigens from Oral Streptococci with Mammalian Tissues and Tissue Components

摘要

This contract examined possible cross-reactive antigens shared by serotypes of Streptococcus mutans and mammalian tissues including heart, skeletal muscle, smooth muscle, kidney, heart and skeletal muscle and strains of serotypes e and g of S. mutans. Initial studies were unable to confirm earlier findings of common antigens shared with all S. mutans serotypes and heart. Because of this a collaborative study was carried out with 3 other laboratories. This also did not confirm eariler reports in the literature.