Secondary and Tertiary Aliphatic Monoamines

摘要

The health effects of occupational exposure to secondary and tertiary aliphatic monoamines are reviewed. The extent and degree of exposure through the natural occurrence of aliphatic amines in the environment and by occupational exposure are discussed. Patterns of worker exposure by occupational are described. The biological effect of exposure on humans are discussed, and the results of six epidemiologic studies are presented. A brief description of the toxic effects observed in animal experiments is provided, and limitations in this type of research are discussed. Metabolism studies of these amines are described, and the minimal extent of biochemical studies is noted. The mutagenic and carcinogenic potential and the reproductive effects of secondary and tertiary monoamines are described.