Automated Gel-Permeation System for Removal of Lipids in Gas Chromatography/Mass Spectrometric Analysis of Fatty Tissues for Xenobiotic Chemicals

摘要

The interference of natural lipids in gas chromatography/mass spectrometric analysis of xenobiotic chemicals in fatty tissue can be substantially reduced using gel-permeation chromatographic removal of the lipids. This paper presents an inexpensive controller which can be used with any manual gel-permeation system to automate the isolation of trace chemicals from lipids. The controller is especially suited for the preparation of large samples required for gas chromatography/mass spectrometric identification of its trace contaminants.