Gene Linkage and Familial Behavioral Characteristics

摘要

The identification of genes influencing behavioral traits by relating the pattern of phenotypes in a family to the transmission of marker genes having a known Mendelian pattern of inheritance was studied. Families selected for two or more siblings with primary affective disorders were typed for HLA and other chromosome 6 genes. It is concluded that genes on chromosome 6 contribute to vulnerability to primary affective disorder.