Atherosclerosis Assessment by Angiographic Image Processing and Ultrasound

摘要

The research has two major goals: (1) To extend the use of image averaging of angiograms to provide non-invasive measures for atherosclerosis assessment; and (2) determination of the physical properties of human arterial tissue relative to the velocity, attenuation, and reflection of ultrasound at physiologically useful frequencies. These goals are to be achieved by radiologic studies in human cadavers which simulate venous injection conditions and contrast these with arterial injection conditions. Additional radiographic studies utilizing the canine model are to be undertaken. Determination of ultrasound physiological properties are to be conducted in human and canine tissue removed at autopsy.