Anticoagulant Bound Hemodialysis

摘要

A totally heparin coated hemodialysis system was used in 7 chronic uremic patients and one acute uremic patient. Tubings were grafted with a chloroform soluble heparincetylpyridinium complex, HFAK was grafted using the cyanogen bromide method. Anticoagulant effect was caused by a micro leakage of heparin from the HFAK and the blood tubing sets. B12 clearance was moderately decreased (22%) by the binding chemistry.