Carcinogenesis Bioassay of Melamine (CAS No. 108-78-1) in F344/N Rats and B6C3F1 Mice (Feed Study)

摘要

A carcinogenesis bioassay of melamine (95% pure), a chemical intermediate in the manufacture of amino resins and plastics, was conducted by feeding diets containing 2,250 or 4,500 ppm melamine to groups of 50 male F344/N rats and 50 B6C3F1 mice of each sex for 103 weeks. Groups of 50 female rats were fed diets containing 4,500 or 9,000 ppm melamine. Groups of 49 male rats, 50 female rats, 49 male mice, and 50 female mice served as controls.