Event-Related Brain Potentials: An Alternative Methodology for Neurotoxicological Research

摘要

One of the problems encountered in studies of glue sniffing, and other types of solvent poisoning is addiction. This problem also afflicts researchers who tend to become addicted to a particular methodology. This paper will review some alternatives to the behavioral methods to which many of us have become addicted. These alternatives include sensory evoked potentials and event-related slow potentials of the brain. Evoked potentials are sensitive, clinically proven, indices of sensory deficits, while event-related slow potentials are sensitive, albeit experimental, indices of cognitive dysfunction. Evidence is accumulating that evoked and slow potential measures may also be sensitive indices of neurotoxic effect.