Enzymatic Approach to Biotransformation

摘要

An overall scheme for the biotransformation of organic compounds by routes other than hydrolysis of possible ester bonds is presented. Both phase I (oxidative) and phase II (conjugative) biotransformation reactions are discussed on an enzyme basis. Whenever possible pesticides are used as examples of the mechanisms by which enzyme activities alter chemical structure (biotransformation) as well as the ways in which chemicals themselves can effect enzyme activities.