Comparison of Nitro-Aromatic Content and Direct-Acting Mutagenicity of Passenger Car Engine Emissions

摘要

This paper describes a study to identify and quantify 23 nitroaromatic compounds in the extracts of particulate material from three light-duty passenger car diesel engines and one gasoline engine. Mutagenic assay data were also collected on these extracts using the Salmonella typhimurium TA98 bioassay without S9 metabolic activation. The results of these two studies were compared to determine whether the concentration of the nitro-aromatics detected can fully account for the direct-acting mutagenic activity indicated by the bioassay data.