Di-n-octylphthalate: Reproduction and Fertility Assessment in CD-1 Mice When Administered in Feed (Revised)

摘要

Di-n-octylphthalate (octoil, Di(2-ethylhexyl)phthalate, bis(2-ethylhexyl)phthalate, dioctylphthalate) is a colorless viscous liquid. When administered orally in mice, LD50 value was 6513 mg/kg. It emits acrid smoke and fumes when heated to decomposition. It is used in vacuum pumps. The reproductive toxicity of di-n-octylphthalate was evaluated according to the Fertility Assessment by Continuous Breeding (FACB) protocol.