Evaluation of Figure-Eight Maze Activity and General Behavioral Development Following Prenatal Exposure to Forty Chemicals: Effects of Cytosine Arabinoside, Dinocap, Nitrofen, and Vitamin A

摘要

The present report describes the effects of prenatal administration exposure of a large number of compounds on the locomotor activity levels of mice. The effects of these treatments on the postnatal growth, viability, morphology and reproductive function from the first experiment have been reported elsewhere (Gray and Kavlock, 1984). Some of the chemicals used in this study are known teratogens in mice, others are known nonteratogens, while a few are unknowns. The results of additional studies on nitrofen, Vitamin A and dinocap are presented because they clearly demonstrate the utility of postnatal behavioral testing. (Copyright (c) 1986 by Intox Press, Inc.)