Review of Research in Support of Extrapolation Models by EPA's (Environmental Protection Agency's) Office of Research and Development

摘要

The report's major finding is that there is no overall, conceptually integrated Environmental Projection Agency (EPA) research program on extrapolation modeling, but a conglomeration of investigator-initiated projects, many of which are commendable in their design and implementation. The major recommendation is that EPA should develop a comprehensive plan for an extrapolation models research program that should: articulate an overall conceptual objective towards which individual projects would aim; enhance EPA's risk assessment-risk management philosophy; develop a framework that promotes more planning and resource stability in support of the research; provide a common nomenclature; improve communication among the Agency's organizational components; and explain to the nonscientist how the research on extrapolation models supports the Agency's regulatory decisions.