Respiratory Responses of Subjects with Allergic Rhinitis to Ozone Exposure and Their Relationship to Nonspecific Airway Reactivity

摘要

Ozone exposure in man produces changes in respiratory function and symptoms. There is a large degree of unexplained intersubject variability in the magnitude of these responses. There is concern that individuals with chronic respiratory diseases may also be more responsive to ozone than normal individuals. The purpose of the study was to describe the responses of subjects with allergic rhinitis to ozone exposure and to compare these responses to those previously observed in normal individuals. A further purpose was to measure the association between baseline nonspecific airway reactivity and changes in lung function and respiratory symptoms following ozone exposure. (Copyright (c) Toxicology and Industrial Health, Vol. 3, No. 4, 1987.)