Role of NADH and NADPH in Dissimilatory Processes in 'Desulfovibrio' Strains

摘要

The thesis deals with some physiological and biochemical aspects of the genus Desulfovibrio, the longest known and best characterized among the sulfate-reducing bacteria. The work described mainly focused on the role of NAD and NADP as electron carriers in the energy metabolism of Desulfovibrio. Until 1986, pyridine nucleotides, which play such a central role in anabolism as well as catabolism of heterotrophic aerobes, were considered not to be involved in dissimilatory processes in Desulfovibrio. The dissimilatory pathways of substrates in which NAD(P)H-producing reaction possibly are involved were investigated and the possible mechanisms of electron transfer from NAD(P)H to the sulfate reduction process were studied.