Cell Biological Aspects of the Control of Gonadotropin Release in the African Catfish, 'Clarias gariepinus' (Celbiologische Aspecten van de Regulatie van Gonadotropine-Afgifte in de Afrikaanse Meerval, 'Clarias gariepinus')

摘要

The release of GTH from gonadotropic cells in the pituitary of the African catfish is controlled by at least two hypothalamic factors. It is stimulated by gonadotropin-releasing hormone (GnRH) and inhibited by dopamine. In addition, a feedback by gonadal steroids has been observed. One of the aims of the investigations, carried out by the Research Group for Comparative Endocrinology of the University of Utrecht, is to reveal the mechanisms of interaction between these multiple input signals, resulting in a single output: the controlled release of GTH.