Thrombotic Thrombocytopenic Purpura (TTP): Like Illness Associated with Intravenous Opana ER Abuse: Tennessee, 2012. Morbidity and Mortality Weekly Report, Volume 62, Number 1.

摘要

On August 13, 2012, three cases of unexplained thrombotic thrombocytopenic purpura (TTP)like illness were reported to the Tennessee Department of Health (TDH). The three patients were intravenous drug users who resided in a rural county in northeast Tennessee. By the end of October, TDH had identified 15 such cases. A case-control study was conducted, and investigators determined that the cases of TTP-like illness were associated with dissolving and injecting tablets of Opana ER, a recently reformulated extended-release form of oxymorphone (an opioid pain reliever) intended for oral administration.