Synthesis of 4-((((Isopropyloxy)methylphosphoryloxy)imino)methyl)-1-methylpyridinium Iodide and Its Characterisation

摘要

Oximes are used in the therapy of organophosphate poisoning. They form aninteraction product with the organophosphate which is claimed to be more toxic than the organophosphate itself. The authors have synthesized one of these compounds which would be formed by the reaction of pyridine-4-carbaldehyde oxime methiodide with sarin (GB). Thus, reaction oxime with sarin chloridate yielded 4-