Synthesis of Derivatives of Glucose-4-phosphoric Acid.

摘要

During the course of an investigation of biochemical mechanisms forming glucosidic linkages it became desirable to secure glucose-4-phosphoric acid for use as a substrate. In our work, Raymond's synthesis resulted in very poor yields. The synthesis described by the present authors utilizes a novel rearrangement first described by Helferich and Klein and the convenient phosphorylating agent diphenylchlorophosphonate. jg p.1.