ANALYSIS OF PHYSIOLOGICAL SYSTEMS BY PARAMETER ESTIMATION TECHNIQUES

摘要

Physiological systems belong to the class of "difficult systems", about which little a priori information exists. If information is available, it may often be difficult to express mathematically. First some basic notions are formalized, like state and optimal state. Using these notions we progress to develop some models of the patient's system and we will indicate when they can be useful. The ultimate goal is to predict the patient's reaction to drug administration quantitatively in order to apply a therapy that is in some way optimal.