The Effect of Atp on Survival in Intestinal Ischemia Shock, Hemorrhagic Shock, and Endotoxin Shock in Rats

摘要

A dose of Mg-ATP (72 micro/mole/kg) was injected into anesthetized rats, subjected to intestinal ischemia shock, hemorrhagic shock, or endotoxin shock, shock models in which all untreated animals died. Administration of Mg-ATP in no instance improved survival rate. It is concluded that any beneficial effect of ATP is probably small while the occurrence of adverse effects cannot be neglected.