Use of supercritical carbon dioxide fluid as a solvent for the purification of pet radiotracers

摘要

We have identified superfluid chromatography (SFC) as a promising method which could offer advantages in radiotracer purification through rapid separation, as well as, improved recovery and purity of labeled product. Using SF CO(sub 2) as the mobile phase for chromatographic separation of labeled product would eliminate the need for solvent removal from product prior to delivery.