Development of MAG3 p-nitrophenyl ester for technetium-99m and rhenium-188 labeling of amines and peptides

摘要

Conjugate labeling by active ester chemistry is a well-established method for labeling peptides and proteins with technetium and rhenium. The easy preparation and high conjugations yields presented in this paper show that both (sup 188)Re and (sup 99m)Tc-MAG(sub 3) p-nitrophenyl esters are promising agents for labeling a wide range of biomolecules for radio therapy or diagnostic imaging.