首页> 美国政府科技报告 >Report on the results of research and development under a consignment from NEDO of glycoconjugate production utilizing technologies. Development of technologies to fix and effectively utilize carbon dioxide by applying glycoconjugates.
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Report on the results of research and development under a consignment from NEDO of glycoconjugate production utilizing technologies. Development of technologies to fix and effectively utilize carbon dioxide by applying glycoconjugates.

机译:报告NEDO委托使用技术进行糖缀合物生产的研究和开发结果。开发通过应用糖缀合物来固定和有效利用二氧化碳的技术。

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This paper reports research results in fiscal 1997 for the 'research and development of glycoconjugate production utilizing technologies'. In synthesizing, utilizing and remodeling technologies for glycoconjugates by means of chemical synthesis, studies were performed on developing methods to synthesize Gal (beta)1-3Gal NA(c (alpha))1-0-Serine in preparative scale, synthesizing high mannose type sugars of natural type without protection groups, and linking GlcNA or GalNAc onto partial peptide of fibroblast growth factor (FGF). In synthesizing, utilizing and remodeling technologies for glycoconjugates by using biological methods, studies were carried out, with regard to glycoconjugate synthesizing, utilizing and remodeling technologies utilizing animal cells, on identifying sugar structures of IFN-(gamma) produced from CHO cell line, and isolating CHO cell lines introduced with genes of sugar transferred enzyme GnTIV and/or GnTV. Furthermore, studies were conducted on glycoconjugate synthesizing, utilizing and remodeling technologies utilizing microorganisms, and glycoconjugate structure analyzing technologies. In addition, overall investigation was made on glycoconjugate production utilizing technologies. 113 refs., 76 figs., 18 tabs.

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