THE EARLY FATE OF POLONIUM210 IN CATS. GASTROINTESTINAL ADMINISTRATION STUDIES. II. INTRAVENOUS ADMINISTRATION STUDIES.

摘要

The absorption, distribution and excretion of polonium210 citrate and neutralized polonium210 chloride from isolated in vivo stomach pouches and intestinal segments and following intravenous administration have been studied up to twelve hours. The experiments were designed to differentiate some of the effects of varying the dose, form, and absorption site of polonium by the use of tissue analyses, serial blood, bile, and urine analyses, and autoradiography. Significant absorption of polonium from the cat stomach occurs irrespective of the chemical form of polonium administered. The rate of absorption of ionic polonium from the intestine exceeds that for polonium colloid by a factor of ten.