Anaesthetized dogs were scalded by immersion in hot water, and determinations were made, before and after the burns, of cardiac output, liver blood flow, blood volume, ECG and pulse contours. Prompt and severe reductions in cardiac output and marked decreases in liver blood flow were observed and severe ECG and pulse disturbances were found. Plasma volume losses appeared to be inadequate to account for the marked changes observed. Early myocardial depression as one possible cause of these changes is discussed.
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