PROCEDURE FOR THE RADIOCHEMICAL ANALYSIS OF STRONTIUM AND BARIUM IN HUMAN URINE

摘要

An analytical procedure for the determination of radioactive strontium and barium in large volumes of urine is described. The method is based on the preferential chelation of calcium over strontium using versene. This difference is greatest at a pH of 4.5 to 6.0. When a versenate chelate of the alkaline earths in a urine specimen, at a pH of 5.5, is passed over a cation exchange column all of the strontium and barium is adsorbed, whereas almost all of the calcium and about l/2 of the magnesium passes into the effluent as the chelate. The extraneous calcium and magnesium can be removed from the resin with a solution of citric acid and versene at a pH of 5.0. The sodium is removed with 0.5N HC1, while the radioactive strontium and barium is eluted with 6N HNO3.