This is due probably to tritium in the side chain, the tritium in the benzene nucleus being expected to form a stable label as a result of the deactivating influence of the nitrogroup.nMoreover, it is found that in the organism chemical reactions take place by which the side chain is altered. Tritium in the side chain could be split off by these chemical reactions and introduced into other molecules.nConsequently it is of interest to synthetize chloramphenicol exclusively tritiated in the aromatic nucleus.
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