CONTROL OF RAT TESTICULAR MONOAMINE OXIDASE (MAO) ACTIVITY:HYPOFHYSECTOMY, ADRENALECTOMY, FSH, LH, PROLACTIN, HCG, AND TESTOSTERONE1

摘要

Monoamine oxidase activity (MAO) was measured in male rats using homogenized testicular tissue preparations. Rats were subjected to hypophysectomy, adrenalectomy, and treatment with HCG, FSH, LH, Prolactin, or a combination of FSH, LH, and Prolactin. Hypophysectomy of male rats at three or ten weeks of age significantly reduced testicular MAO activity when these animals were compared with controls. HCG treatment in hypophysectomized animals significantly Increased androgen synthesis and prostate and seminal vesicle weights, but had no effect on MAO activity. Treatment with FSH, LH, or a combination of FSH, LH, and Prolactin increased MAO activity in hypophysectomized animals. FSH was the most effective in increasing testicular MAO activity. Adrenalectomy had no effect on MAO activity.