Average Number of Generations Until Extinction and Rate of Allelism of Lethal Genes in a sub-Divided Population

摘要

The expected number of generations until extinction of a lethal gene was studied by a Markov chain method for two partially isolated populations of Drosophila whose sizes are N sub 1 and N sub 2 . A simulation study was done for larger population sizes. The extinction time depends strongly on the asymmetry of N sub 1 and N sub 2 , the size of the population in which the new lethal mutant arises, and the number of migrants per generation. If N sub 1