Studies on Metabolic Antigen of F. Hepatica. Part of a Coordinated Programme on Isotopes and Radiation in Animal Parasitology and Immunology. Final Report for the Period 1 April 1974--31 December 1976

摘要

The final report submitted by Dr. Cuperlovic covers research findings on the immunological mechanisms and responses involved in liver fluke (Fasciola hepatica) infections in rabbits and sheep. Series of experiments were carried out to test the immunogenecity of labelled fluke tissue-fractions in rabbits. Hyperimmunization with secretory-excretory antigens gave conflicting results and it was concluded that only a very limited immunity is being conferred. Trials with anti-liver antibodies suggest that even autoimmune processes are involved. (Atomindex citation 08:347048)