A Preliminary Toxicological Study of Silastic 386 Foam Elastomer:Catalyst

摘要

The acute oral LD30/50 values in mice and rats for cured Slapstick 386 (95 parts foam elastomers plus 5 parts catalyst) were greater than 5 g/kg. According to classical guidelines, the mixture would be considered slightly toxic or practically nontoxic in both species. Skin application studies in the rabbit demonstrated the mixture to be mildly irritating. Eye irritation studies, also in the rabbit, showed the cured Slapstick 386 to be a mild but transitory irritant. The sensitization study in the guinea pig did not demonstrate the mixture to be a sensitizer.