Bone Blood Flow Measured by exp 41 Ar Clearance Formed by exp 44 Ca(N, alpha ) exp 41 Ar

摘要

A technique to measure regional inert gas washout in bone, in vivo, by measuring exp 41 Ar clearance formed by fast-neutron activation of exp 44 Ca has been developed. Following fast-neutron irradiation of whole rats, the perfusion-limited clearance of exp 41 Ar was measured for both dead and living rats. The clearance rate for the live rats indicate that the bone perfusion is in the range of 3 to 20 ml/100 Argon distribution volume. (ERA citation 08:052376)