Case-Control Study of Brain Tumors among White Males Employed at the Rocky Flats Plant

摘要

We conducted a case-control study of 16 primary brain tumor deaths occuring among white males employed at the Rocky Flats Plant during 1952 to 1980 to investigate the relationship between these tumor cases and occupational radiation/nonradiation exposures. Three mutually exclusive control groups were selected from the white male employees: matched (individually matched on age and period of employment), deceased, and random. Each group consisted of a 4:1 control-case ratio. Analyses for exposure to internally deposited plutonium and external penetrating radiation were based on health physics dosimetry measurements. Potential exposure to nonradiation hazards was analyzed by job title and work area. Because evidence of exposure to beryllium and uranium existed in only one case, we did not analyze for these exposures. Our study showed no statistically significant association between exposure to internal radiation and brain tumor. We found no statistically significant differences in external radiation exposure between the tumor cases and the three control groups. In addition, no nonradiation occupational risk factors were identified. (ERA citation 08:044800)