Picogram FT-IR: Ultramicrosampling and GC-IR

摘要

The commonality between ultramicrosampling and GC-IR is far deeper than the desire for picogram detection levels in both cases. Both techniques also need small area light spots: in ultramicrosampling, for spatial resolution; and in GC-IR, to match limited sample volumes. Fast response is needed for real-time measurements on the fly GC-IR, and for mapping analysis of extended samples in a finite line in ultramicrosampling. And finally, the fly fast processing is required for real-time recognition of significant success in GC-IR (presence of peaks) and in ultramicrosampling (presence of local anomatlies in sample). A small FT-IR interferometer benefiting from the counter-Jacquinot advantage, immersion optics for microsampling and optimized sample cells for GC-IR, high efficiency sources and detectors and the systematic application of information theory to data processing algorithms can be used to bring both these techniques into the middle picogram domain. 8 figs. (ERA citation 10:051926)