Upgrading Coal-Derived Liquids by Means Other Than Hydrotreatment. 2. Tumorigenicity and Tumorigens

摘要

Distillation was confirmed to be a generally desirable first step in upgrading coal-derived liquids. Not only bactericidal mutagenicity, but also tumorigenicity (as gauged by a ten-animal time-to-tumor assay) is segregated into the vacuum gas oil fraction (boiling range >343 exp 0 C (650 exp 0 F)). Three non-hydrotreating processes (acid treatment, deasphalting, and furfural extraction) were found ineffective in reducing known tumorigens (especially benzo(a)pyrene) and tumorigenicity of the vacuum gas oil fraction. The benzo(a)pyrene content of the treated products (but not their mutagenicity) was found to be qualitative indicator for skin tumorigenicity. Two novel nonhydrotreatment processes, a three-step oxidation and NaOH treatment at elevated temperature and pressure, were investigated and found to have little utility in removing benzo(a)pyrene. 11 refs., 7 tabs. (ERA citation 10:026621)