Longitudinal Emission Tomography of Thyroid and Heart. A Technical Evaluation of Three Imaging Devices

摘要

In this thesis three devices are discussed for longitudinal emission tomography, one of which has been developed for myocardial imaging and the other two for thyroid imaging. Longitudinal emission tomography is a technique which enables three-dimensional reconstruction of the radioactivity distribution within an organ from two-dimensional distributions on a detector surface. In Ch. 1 a general survey is given of the clinical environment in which the devices will be used. Ch. 2 discusses a well-known technique for myocardial imaging: seven-pinhole tomography. In Ch. 3 this technique is applied to imaging of the thyroid. Three different reconstruction methods have been applied to the data collected with the system (from phantoms as well as from patients) and the results have been evaluated. Ch. 4 discusses simulation studies which were carried out in order to investigate the potentialities of a time-coded aperture (TCA) system designed for thyroid tomography. In Ch. 5 a prototype is tested of the time coded aperture in a clinical environment. The last chapter presents a comparison between the (thyroid) 7P collimator and the TCA device. (Auth.). Includes Dutch summary. (Atomindex citation 18:079929)