Photoreactivation in Escherichia coli phr-1 Mutants.

摘要

Photoreactivation (PR) has been observed in E. coli phr-1 mutants by several investigators, contradicting the consensus that these strains are completely PR deficient. Several theories have been advanced regarding the nature of this photorepair, including the possible existence of a second photolyase enzyme. Our studies confirm the finding that PR occurs in phr-1 mutants and in light of recent observations on the nature of the 6-4 photoproduct, support the theory that photolysis of this lesion leads to the increased survival we have witnessed. Results are briefly discussed. 13 refs., 1 fig., 1 tab. (ERA citation 14:020666)