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Initial Submission: Ls 840606: Preliminary Toxicity Study in Beagle Dogs by Repeated Oral Administration for 28 Days with Cover Letter dated 052192.

机译：初步提交：Ls 840606：Beagle犬的初步毒性研究，通过重复口服给药28天，求职信日期为052192。

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年度 1992
页码 1-254
总页数 254
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Toxicology; Health effects; Rhone-poulenc inc; Toxic substances; Ls 8840606; Laboratory animals; Subchronic toxicity; Mammals; Dogs; Oral; Gavage; CAS No. 112839-32-4;

机译：毒理学;健康影响; Rhone-poulenc inc;有毒物质; Ls 8840606;实验动物;亚慢性毒性;哺乳动物;狗;口服;灌胃; Cas No. 112839-32-4;

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1. Evaluation of subchronic toxicity of GRD081, a dual PI3K/mTOR inhibitor, after 28-day repeated oral administration in Sprague-Dawley rats and beagle dogs [J] . XiaZ., GaoT., ZongY., Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research . 2013,第Null期

机译：在Sprague-Dawley大鼠和beagle犬重复口服28天后，评估PI3K / mTOR双重抑制剂GRD081的亚慢性毒性
2. Evaluation of subchronic toxicity of SIM010603, a potent inhibitor of receptor tyrosine kinase, after 28-day repeated oral administration in SD rats and beagle dogs [J] . Yu Mao, Zhenna Xia, Xiaofang Zhang, Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research . 2012,第5期

机译：重复28天在SD大鼠和比格犬中口服后，评估受体酪氨酸激酶的有效抑制剂SIM010603的亚慢性毒性
3. Evaluation of subchronic toxicity of SIM010603, a potent inhibitor of receptor tyrosine kinase, after 28-day repeated oral administration in SD rats and beagle dogs [J] . Yu Mao, Zhenna Xia, Xiaofang Zhang, Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research . 2012,第5期

机译：SIM010603的次级毒性评价，一种受体酪氨酸激酶的有效抑制剂，在SD大鼠和比格犬中重复口服给药后28天后
4. Empty Biovector~(TM) Toxicity Studies by Nasal Administration in rabbits and Beagle Dogs [C] . R.Kravtzoff, O Loget, X. Manciaux, International symposium on controlled release of bioactive materials;Consumer and diversified products conference . 1998

机译：鼻腔给药对兔子和比格犬的空Biovector〜（TM）毒性研究
5. GMP-grade α-TEA lysine salt: a 28-Day oral toxicity and toxicokinetic study with a 28-Day recovery period in Beagle dogs [O] . Bella S. Guerrouahen, Tobias Hahn, Zefora Alderman, 2016

机译：GMP级α-TEA赖氨酸盐：对Beagle犬进行28天的口服毒性和毒代动力学研究恢复期为28天
6. GMP-grade α-TEA lysine salt: a 28-Day oral toxicity and toxicokinetic study with a 28-Day recovery period in Beagle dogs [O] . Bella S. Guerrouahen, Tobias Hahn, Zefora Alderman, 2016

机译：GMP级α-TEA赖氨酸盐：对Beagle犬进行28天的口服毒性和毒代动力学研究，恢复期为28天
7. Initial Submission: Ls 840606: Subchronic Toxicity Study in Dogs (final Report) with Cover Letter dated 052192. [R] . 1992

机译：初步提交：Ls 840606：狗的亚慢性毒性研究（最终报告），求职信日期为052192。

Initial Submission: Ls 840606: Preliminary Toxicity Study in Beagle Dogs by Repeated Oral Administration for 28 Days with Cover Letter dated 052192.

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