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Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives.

机译：吡咯烷甲基-2-氨基吡啶衍生物的设计合成探讨神经元型一氧化氮合酶的活性部位。

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作者
H. Ji H. Li L. J. Roman P. Martasek R. B. Silverman S. L. Delker T. L. Poulos;
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年度 2010
页码 1-21
总页数 21
原文格式 PDF
正文语种 eng
中图分类工业技术;
关键词
Amines; Design; Enzymes; Neurodegenerative disorders; Nitric oxide; Pyridines; Pyrrolidines; Synthesis(Chemistry); Therapy;

机译：胺类;设计;酶;神经退行性疾病;一氧化氮;吡啶类;吡咯烷类;合成（化学）;治疗;
入库时间 2022-08-29 10:49:51

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1. Exploration of the active site of neuronal nitric oxide synthase by the design and synthesis of pyrrolidinomethyl 2-aminopyridine derivatives [J] . Ji H., Delker S.L., Li H., Journal of Medicinal Chemistry . 2010,第21期

机译：通过设计和合成吡咯烷基甲基2-氨基吡啶衍生物探索神经元一氧化氮合酶的活性位点
2. Design and Synthesis of C5 Methylated L-Arginine Analogues as Active Site Probes for Nitric Oxide Synthase [J] . Nathaniel I. Martin, Joshua J. Woodward, Michael B. Winter, Journal of the American Chemical Society . 2007,第41期

机译：一氧化氮合酶活性位点探针C5甲基化的L-精氨酸类似物的设计与合成
3. Novel and orally bioavailable inducible nitric oxide synthase inhibitors: synthesis and evaluation of optically active 4,5-dialkyl-2-iminoselenazolidine derivatives. [J] . Ueda S, Terauchi H, Suzuki K, Bioorganic and Medicinal Chemistry Letters . 2005,第5期

机译：新型和口服生物可利用的诱导型一氧化氮合酶抑制剂：合成和光学活性的4,5-二烷基-2-亚氨基硒唑烷衍生物的评估。
4. Mapping Calmodulin-induced Conformational Changes During Activation of Neuronal Nitric Oxide Synthase by H/D Exchange Mass Spectrometry. [C] . Brian C. Smith, Eric S. Underbakke ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：H / D兑换质谱法在神经元一氧化氮合酶激活过程中诱导钙调蛋白诱导的构象变化。
5. NG-nitro-L-arginine-containing peptidomimetics as selective neuronal nitric oxide synthase inhibitors. Structure-based design, synthesis, and biological evaluation and approaches toward enhanced CNS activity. [D] . Seo, Jiwon. 2006

机译：含NG-硝基-L-精氨酸的拟肽作为选择性神经元一氧化氮合酶抑制剂。基于结构的设计，合成和生物学评估以及增强CNS活性的方法。
6. Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives [O] . Haitao Ji, Silvia L. Delker, Huiying Li, -1

机译：通过吡咯烷2-氨基吡啶衍生物的设计与合成神经元型一氧化氮合酶的活性位点的探索
7. Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives [O] . Richard B. Silverman 2010

机译：吡咯烷甲基-2-氨基吡啶衍生物的设计合成探讨神经元型一氧化氮合酶的活性部位

Exploration of the Active Site of Neuronal Nitric Oxide Synthase by the Design and Synthesis of Pyrrolidinomethyl 2-Aminopyridine Derivatives.

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